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Anne Rice (born Howard Allen O'Brien on October 4, 1941), the second daughter of an Irish Catholic family, is an author of horror/fantasy stories, often about vampires, mummies and witches. Her works have been a major influence on the Goth youth subculture, and she has published several works with sado-masochistic themes. She was married to the late poet Stan Rice and is the mother of gay novelist Christopher Rice.

She was born and has spent most of her life in New Orleans, Louisiana, the city that forms the background against which most of her stories take place. Known for her avid interest in art and culture, she and her family occasionally took trips overseas to study the art which would later be mentioned in her stories.

Rice has also published under the pen names Anne Rampling and A.N. Roquelaure, the latter of which was used primarily for more adult-oriented material. Her fiction is often described as lush and descriptive, and her characters' sexuality is fluid, often displaying homoerotic feelings towards each other.

She completed her first book, Interview with the Vampire, in 1973 and published it in 1976. In 1994, Neil Jordan directed a motion picture by the same name loosely based on the story. Following that a second movie was made, which used as its inspiration the 3rd book in the original Vampire Chronicles' series, Queen of the Damned, skipping the 2nd one. At one point in the past, a rather funny film version of her adult book Exit to Eden was also created, starring a then lesser-known Rosie O'Donnell and Dan Aykroyd.

Rice has adult onset diabetes mellitus. This was discovered when she went into a diabetic coma in December of 1998. She has since been treating the condition with insulin, and is an advocate for people to get tested for diabetes.

On 30 January 2004 Rice announced her plans to leave her home town of New Orleans, to move to a gated home in the suburb of Jefferson Parish, Louisiana. She had already put the largest of her three homes in Uptown New Orleans up for sale, and plans to sell the other two. She cited living alone since the death of her husband and her son's moving out of state. "Simplifying my life, not owning so much, that's the chief goal, said Rice, I'll no longer be a citizen of New Orleans in the true sense." Some have speculated that Rice also wished for more privacy from the constant attentions of her fans, some of whom were known to camp out in front of her house; sometimes up to 200 or more would gather to see her leave for church on Sundays.