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Chris Messina marks a reunion with director-screenwriter Nora Ephron in Julie & Julia. One of his earliest film appearances was in a bit part in Ephron's 1998 romantic comedy You've Got Mail. Messina can currently be seen starring alongside John Krasinski and Maya Rudolph in Sam Mendes' Away We Go, where his performance has garnered him critical praise. Last year he rounded out an all star cast of Woody Allen's award winning Vicky Cristina Barcelona.

Messina will also star in several upcoming movies including Monogamy opposite Rashida Jones, Greenberg with Ben Stiller, and An Invisible Sign alongside Jessica Alba. Messina came to national attention in 2005 during the final season of HBO's acclaimed series Six Feet Under, in which he was cast opposite Lauren Ambrose. He drew further notice as Ira in the popular indie romance Ira and Abby, co-starring Jennifer Westfeldt, and in 2007 was listed as one of Variety's Ten Actors to Watch.

His other films include Humboldt County, Made of Honor, and Alan Ball's Towelhead. Messina has worked extensively on the New York stage. He appeared on Broadway with Al Pacino and Marisa Tomei in Oscar Wilde's Salome, and starred opposite Frances McDormand under the direction of Stephen Daldry in New York Theatre Workshop's production of Caryl Churchill's Far Away.

Other notable stage appearances include Blur(Manhattan Theater Club), Good Thing (The New Group), Adam Rapp's Faster, This Thing of Darkness (Atlantic Theatre Company), and Frank Pugliese's Late Night, Early Morning, which premiered at the Tribeca Theatre Festival and went on to win the Jury Award for Best Theatre at the 2005 Aspen Comedy Festival.