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Cristine Rose stars in NBC's Emmy Award-nominated ensemble drama series Heroes as the mysterious, calculating NY matriarch Angela Petrelli, who is willing to sacrifice anything, including her gifted sons Nathan (Adrian Pasdar) and Peter (Milo Ventimeglia), to change the world. She and her late husband were part of a core group of special individuals associated with The Company. Heroes follows the lives of ordinary people who discover they possess extraordinary abilities.

Rose has performed on stage, in film, and on television. Series roles include Mrs. Bueller in NBC's Ferris Bueller and Mrs. Barash in Flying Blind. Recurring roles include Lydia Brock on Picket Fences, Cynthia Blake on Providence, and Bitsy Hannigan on Friends. Recently, she has been featured on How I Met Your Mother and Big Love.

After graduation from Stanford University, Rose spent many years devoted to the stage. In New York, she starred in Wendy Wasserstein's long-running hit Isn't It Romantic? at Playwrights Horizons; and played Elfriede in Richard Foreman's production of Three Acts of Recognition at Joe Papp's Public Theatre.

She has performed at several regional theatres, including the Guthrie Theatre where she played the Countess in Andre Serban's acclaimed production of The Marriage of Figaro, as well as Yelyena in Uncle Vanya, directed by Garland Wright. Her most recent foray onto the stage was in Charles Mee's A Perfect Wedding, directed by Gordon Davidson as the inaugural production of the Kirk Douglas Theatre in Los Angeles.

In 2007, Rose received her Master of Arts degree in theatre with distinction from California State University, Northridge. She managed to interweave her television work with classes, papers, and presentations. Her master's thesis centered on the actor's role in American new play development, for which she criss-crossed the country, interviewing 21 accomplished directors and playwrights, including Pulitzer Prize winners Lanford Wilson, Wendy Wasserstein, Lee Blessing, and Donald Margulies.