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Matthew Settle stars as Rufus Humphrey in The CW's hit drama Gossip Girl, from Josh Schwartz and Stephanie Savage (The O.C.), based on the tremendously popular book series about privileged teenagers in New York City.

Settle starred as lead character Jacob Wheeler in 2005's TNT six-week television event, Into the West, from executive producer Steven Spielberg. The series was nominated for 16 Emmy Awards. He is also known for his unforgettable role as Capt. Ronald Speirs in HBO's Golden Globe and Emmy award-winning mini-series Band of Brothers. Other television credits include Brothers & Sisters, The Practice and ER.

In film, Settle will next star in Ex-Terminators, with Jennifer Coolidge and Heather Graham. Past film credits include Callie Khour's film adaptation of Divine Secrets of the Ya-Ya Sisterhood, in which he starred opposite Ashley Judd, Jonathan Mostow's WW11 submarine drama U-571, and a critically lauded portrayal of Warren Beatty in Peter Bogdanovich's The Mystery of Natalie Wood.

Born in North Carolina, Settle moved to New York City at age 18 to pursue acting. There his talent was recognized by the legendary producer/lawyer Jay Julien, whose clients included such brilliant locals as Martin Scorsese, Robert De Niro, Harvey Keitel and Christopher Walken. Julien awarded Settle a three-year scholarship with renowned acting teacher William Esper, which in turn led to Settle's first role in Louis L'Amour's Shaughnessy for CBS.

Settle resides with his family in New York City.